Skip to main content
All data dashboards CoVeo App dashboard Dashboards developed by international data services Mpox surveillance Node Dashboards Viralprimer
All visualizations Bee Gut Microbiome
Code Repositories
Data highlights
All datasets CoVEO VCF database Covid Variant Explorer INSDC Mutation on ViralPrimer SARS-COV2 Co-infection SARS-CoV2 RBD Sewage database
All publications Node Publications
All topics Antimicrobial Resistance SARS-CoV-2

SARS-CoV2 RBD - AlphaFold structures

Location

Figshare, https://figshare.com/projects/SARS-CoV-2_RBD_single_mutant_AlphaFold2_structures/150089

Description

AlphaFold2-predicted 3D structures of all single amino acid mutants in the SARS-CoV-2 receptor-binding domain (RBD), enabling structural interpretation of mutation effects.

In this data release paper (“SARS-CoV-2 RBD deep mutational AlphaFold2 structures carry phenotypic information” by Oz Kilim, Anikó Mentes, Balázs Pál, István Csabai and Ákos Gellért) we provide a curated data-set of all single mutations from each of the 7 main SARS-CoV-2 variants.

This results in 3819X7= 26733 pdb structures. We demonstrate that this data is viable for at least some down-steam machine learning tasks implying it contains information that is physically meaningful and structural variation between mutants is somewhat captured appropriately.

  1. SARS-CoV-2 receptor-binding domain deep mutational AlphaFold2 structures
    Kilim et al, 2023, Scientific Data

Coveo